GUIDE
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xyntha
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GUIDE TO
XYNTHA

Guide

guide
to
xyntha

glossary

Common Haemophilia Terms

Albumin
A protein found in human and animal blood.
Antibody
A protein released by the immune system to fight foreign substances that enter the body.
Bleed
Bleeding into muscles, organs and joint spaces.
Clinical Trials
Carefully controlled studies that test the safety and efficacy of medications.
Coagulation
Normal clotting process that arrests bleeding.
Factor
A blood protein involved in the normal clotting process (coagulation); also a shortening of the term ‘factor replacement therapy’, i.e. XYNTHA.
Factor VIII
A clotting factor protein needed for coagulation; low in people with haemophilia A.
Factor IX
A clotting factor protein needed for coagulation; low in people with haemophilia B.
Haemorrhage
Severe bleeding.
Hereditary
Passed on from parents to children through genes.
Infusion
Administration of factor replacement therapy.
Inhibitor
An antibody that neutralises a coagulation factor and interferes with its function, leading to treatment complications.
Nanofiltration
Additional step in the XYNTHA purification process involving a tiny 35 nanometre filter.
On-demand
treatment
Using factor replacement in response to a bleeding episode or injury.
Ports
Devices implanted under the skin to improve vein access; often used in young children.
Prophylaxis
Using factor replacement as a preventative treatment.
Synthetic ligand
Man-made molecule in the XYNTHA purification process.
TRACKER FACTORy
A free program for recording and tracking bleeds and infusions by accessing www.trackerfactory.co.nz
Von Willebrand's
disease (VWD)
Deficiency in the clotting protein called von Willebrand factor.

CONTACT your Haemophilia Treatment Centre.